In this study I examine the religious aspects of Native New England ethnobotany. The study focuses on the role of plants in calendrical cycles, mythology, magic, and rituals and ceremonies. I also focus on the numerous uses of tobacco in Native spirituality, looking at several tribes. In addition to this ethnobotanical data, this study also includes a discussion and analysis of the interpretations of Native American spirituality. I include a discussion of both the negative and positive views, including the concept of 'religious evolution' and the idea that Native traditions are primitive and superstitious, the favorable views of Native religious traditions that praise its holistic worldview, and the 'religious imperialism' that has been an unfortunate consequence of these favorable views. Finally, I discuss ecopsychology as a useful tool for interpreting and learning from Native American traditions that benefits both Natives and non-Natives.