Valid 11/2001 - 01/2002

Aldrich Chemical Co., Inc.
1001 West St. Paul
Milwaukee, WI 53233 USA
Tel: 414-273-3850





             M A T E R I A L  S A F E T Y  D A T A  S H E E T
             
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - - - - - - - -
    CATALOG #:            129542
    NAME:                 ISOVALERIC ACID, 99%
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS - - - - - -
    CAS #:NONE
    MF: C5H10O2
    EC NO:  207-975-3
  SYNONYMS
    ACETIC ACID, ISOPROPYL- * BUTYRIC ACID, 3-METHYL- * DELPHINIC ACID *
    ISOPENTANOIC ACID * ISOPROPYLACETIC ACID * ISOVALERIANIC *
    ISOVALERIANIC ACID * KYSELINA ISOVALEROVA (CZECH) * 3-METHYLBUTANOIC
    ACID * 3-METHYLBUTYRATE * BETA-METHYLBUTYRIC ACID * 3-METHYLBUTYRIC
    ACID *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - - - -
  LABEL PRECAUTIONARY STATEMENTS
    CORROSIVE
    CAUSES BURNS.
    TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
    READILY ABSORBED THROUGH SKIN.
    COMBUSTIBLE.
    STENCH.
    IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
    IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
    IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
    WATER AND SEEK MEDICAL ADVICE.
    WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
    PROTECTION.
    DO NOT BREATHE VAPOR.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - - - -
    IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES OR SKIN WITH COPIOUS
    AMOUNTS OF WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
    CLOTHING AND SHOES.
    ASSURE ADEQUATE FLUSHING OF THE EYES BY SEPARATING THE EYELIDS
    WITH FINGERS.
    IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
    RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
    IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
    CALL A PHYSICIAN.
    WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - - - -
  EXTINGUISHING MEDIA
    CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
    WATER SPRAY.
  SPECIAL FIREFIGHTING PROCEDURES
    WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
    PREVENT CONTACT WITH SKIN AND EYES.
    COMBUSTIBLE.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - - - -
    EVACUATE AREA.
    WEAR SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY
    RUBBER GLOVES.
    ABSORB ON SAND OR VERMICULITE AND PLACE IN CLOSED CONTAINERS FOR
    DISPOSAL.
    VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - - - - -
    REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - - - -
    WEAR APPROPRIATE NIOSH/MSHA-APPROVED RESPIRATOR, CHEMICAL-RESISTANT
    GLOVES, SAFETY GOGGLES, OTHER PROTECTIVE CLOTHING.
    USE ONLY IN A CHEMICAL FUME HOOD.
    SAFETY SHOWER AND EYE BATH.
    FACESHIELD (8-INCH MINIMUM).
    DO NOT BREATHE VAPOR.
    DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
    AVOID PROLONGED OR REPEATED EXPOSURE.
    READILY ABSORBED THROUGH SKIN.
    WASH THOROUGHLY AFTER HANDLING.
    CORROSIVE.
    TOXIC.
    KEEP TIGHTLY CLOSED.
    KEEP AWAY FROM HEAT AND OPEN FLAME.
    STENCH.
    STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - - - -
  APPEARANCE AND ODOR
    COLORLESS LIQUID
  PHYSICAL PROPERTIES
    BOILING POINT:        175 C TO 177 C
    MELTING POINT:      -29 C
    FLASHPOINT                 159 F
    EXPLOSION LIMITS IN AIR:
      LOWER                                    1.5%
    AUTOIGNITION TEMPERATURE:        824 F
    VAPOR PRESSURE:      0.38MM 20 C
    SPECIFIC GRAVITY:     0.937
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - - - - - -
  INCOMPATIBILITIES
    BASES
    OXIDIZING AGENTS
    REDUCING AGENTS
  HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
    TOXIC FUMES OF:
    CARBON MONOXIDE, CARBON DIOXIDE
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - - - -
  ACUTE EFFECTS
    HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
    MATERIAL IS EXTREMELY DESTRUCTIVE TO TISSUE OF THE MUCOUS MEMBRANES
    AND UPPER RESPIRATORY TRACT, EYES AND SKIN.
    INHALATION MAY RESULT IN SPASM, INFLAMMATION AND EDEMA OF THE
    LARYNX AND BRONCHI, CHEMICAL PNEUMONITIS AND PULMONARY EDEMA.
    SYMPTOMS OF EXPOSURE MAY INCLUDE BURNING SENSATION, COUGHING,
    WHEEZING, LARYNGITIS, SHORTNESS OF BREATH, HEADACHE, NAUSEA AND
    VOMITING.
  RTECS #: NY1400000
    ISOVALERIC ACID
  IRRITATION DATA
    SKN-RBT 470 MG OPEN MOD                       UCDS** 1/31/1972
    SKN-RBT 500 MG/24H MOD                        FCTXAV 17,841,1979
    EYE-RBT 940 UG MLD                            UCDS** 1/31/1972
  TOXICITY DATA
    ORL-RAT LD50:2 ML/KG                          UCDS** 1/31/1972
    IVN-MUS LD50:1120 MG/KG                       APTOA6 18,141,1961
    SKN-RBT LD50:310 UL/KG                        UCDS** 1/31/1972
  TARGET ORGAN DATA
    BEHAVIORAL (CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD)
    ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
    (RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR
    COMPLETE INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - - - - -
    DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - - - -
    THIS COMBUSTIBLE MATERIAL MAY BE BURNED IN A CHEMICAL INCINERATOR
    EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
    OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - - - -
    CONTACT ALDRICH CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - - - - -
  EUROPEAN INFORMATION
    CORROSIVE
    R 34
    CAUSES BURNS.
    R 23/24/25
    TOXIC BY INHALATION, IN CONTACT WITH SKIN AND IF SWALLOWED.
    S 45
    IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK MEDICAL ADVICE
    IMMEDIATELY (SHOW THE LABEL WHERE POSSIBLE).
    S 26
    IN CASE OF CONTACT WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF
    WATER AND SEEK MEDICAL ADVICE.
    S 36/37/39
    WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
    PROTECTION.
    S 23
    DO NOT BREATHE VAPOR.
  REVIEWS, STANDARDS, AND REGULATIONS
    OEL=MAK
    NOHS 1974: HZD 84451; NIS 2; TNF 35; NOS 2; TNE 69
    NOES 1983: HZD 84451; NIS 4; TNF 148; NOS 16; TNE 6695; TFE 1037
    EPA TSCA SECTION 8(B) CHEMICAL INVENTORY
    EPA TSCA SECTION 8(D) UNPUBLISHED HEALTH/SAFETY STUDIES
    EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - - - - -
    THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
    BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
    FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
    OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
    PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
    COPYRIGHT 2001 SIGMA-ALDRICH CO.
    LICENSE GRANTED TO MAKE UNLIMITED PAPER COPIES FOR INTERNAL USE ONLY