**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****
MSDS Name: Ethylene Glycol
Catalog Numbers:
AC410010040, AC410010200, S80005, S80005-1,
S80005-2, BP230 1, BP230 4,
BP230-1, BP230-4, BP2301, BP2304, E177 20, E177
4, E177-20, E177-4, E17720,
E1774, E178 1, E178 200, E178 4, E178 500, E178-1,
E178-200, E178-4,
E178-500, E1781, E178200, E178200001, E1784,
E1784LOT003, E178500, E178J4,
S79007, S800051, S800052, ZZE1785C15
Synonyms:
1,2-Dihydroxyethane, 1,2-Ethanediol, Ethylene
alcohol, Ethylene
dihydrate.
Company Identification: Fisher Scientific
1 Reagent Lane
Fairlawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS#
|
Chemical Name
| % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 107-21-1 |Ethylene glycol
| >99.0 | 203-473-3 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols:
XN
Risk Phrases:
22
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Appearance: clear, colorless.
Warning! Hygroscopic. This substance has caused adverse reproductive
and fetal effects in animals. May cause kidney damage. May cause
central nervous system effects. May cause eye and skin irritation.
May cause respiratory and digestive tract irritation. May cause
cardiac disturbances. Harmful or fatal if swallowed.
Target Organs: Kidneys, heart, central nervous system.
Potential Health Effects
Eye:
May cause moderate
eye irritation.
Skin:
May cause skin
irritation. Low hazard for usual industrial handling.
Ingestion:
May cause nausea
and vomiting.
Toxicity follows
3-stage progression. (1) involves central nervous
system effects
including paralysis of eye muscles, convulsions, and
coma. Metabolic
acidosis and cerebral swelling may also occur. (2)
involves cardiopulmonary
system with symptoms of hypertension, rapid
heart beat, and
possible cardiac failure. (3) involves severe kidney
abnormalities
including possible renal
Inhalation:
May cause respiratory
tract irritation. Heated or misted substance
may cause headache,
irregular eye movements, and possible coma.
Chronic:
May cause kidney
injury.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush
eyes with plenty of water for at least 15 minutes,
occasionally lifting
the upper and lower eyelids. Get medical aid
immediately. Do
NOT allow victim to rub or keep eyes closed.
Skin:
Flush skin with
plenty of soap and water for at least 15 minutes
while removing
contaminated clothing and shoes. Get medical aid if
irritation develops
or persists. Wash clothing before reuse.
Ingestion:
If victim is conscious
and alert, give 2-4 cupfuls of milk or water.
Never give anything
by mouth to an unconscious person. Get medical
aid immediately.
Inhalation:
Remove from exposure
to fresh air immediately. If not breathing,
give artificial
respiration. If breathing is difficult, give oxygen.
Get medical aid
if cough or other symptoms appear.
Notes to Physician:
Ethanol may inhibit
methanol metabolism.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire,
wear a self-contained breathing apparatus in
pressure-demand,
MSHA/NIOSH (approved or equivalent), and full
protective gear.
Vapors may be heavier than air. They can spread
along the ground
and collect in low or confined areas.
Extinguishing Media:
In case of fire,
use water, dry chemical, chemical foam, or
alcohol-resistant
foam. Water or foam may cause frothing. Use agent
most appropriate
to extinguish fire.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective
equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with
inert material, (e.g., dry sand or earth), then
place into a chemical
waste container. Remove all sources of
ignition. Provide
ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly
after handling. Remove contaminated clothing and
wash before reuse.
Use with adequate ventilation. Ground and bond
containers when
transferring material. Avoid contact with eyes, skin,
and clothing.
Avoid ingestion and inhalation.
Storage:
Keep away from
sources of ignition. Store in a cool, dry,
well-ventilated
area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate general
or local exhaust ventilation to keep airborne
concentrations
below the permissible exposure limits.
Exposure Limits
+--------------------+-------------------+-------------------+-----------------+
| Chemical Name |
ACGIH |
NIOSH |OSHA - Final PELs|
|--------------------|-------------------|-------------------|-----------------|
| Ethylene glycol |aerosol: C 100
|no established |none listed
|
|
| mg/m3
| RELs - see |
|
|
|
|Appendix D |
|
+--------------------+-------------------+-------------------+-----------------+
OSHA Vacated PELs:
Ethylene glycol:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator
when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State:
Liquid
Appearance:
clear, colorless
Odor:
odorless
pH:
Not available.
Vapor Pressure:
.05 mm Hg @ 20C
Vapor Density:
2.1 (air=1)
Evaporation Rate:
Not available.
Viscosity:
21cP @ 20 deg C
Boiling Point:
195 deg C @ 760.00mm Hg
Freezing/Melting Point: -13 deg C
Autoignition Temperature: 410 deg C ( 770.00 deg F)
Flash Point:
111 deg C ( 231.80 deg F)
NFPA Rating:
(est.) Health: 1; Flammability: 1; Reactivity: 0
Explosion Limits, Lower: 3.20 vol %
Upper: 15.30 vol %
Decomposition Temperature:
Solubility:
soluble in water
Specific Gravity/Density: 1.1200g/cm3
Molecular Formula:
C2H6O2
Molecular Weight:
62.06
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room
temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
Incompatible materials,
ignition sources, moisture, excess heat.
Incompatibilities with Other Materials:
Chlorosulfonic
acid, dimethyl terephthalate, oleum, phosphorus
pentasulfide,
silvered-copper wire, sodium hydroxide, sulfuric acid,
titanium butoxide.
Causes ignition at room temperature with chromium
trioxide, potassium
permanganate, and sodium peroxide. Causes
ignition at 100C
with ammonium dichromate, silver chlorate, sodium
chloride, and
uranyl nitrate.
Hazardous Decomposition Products:
Carbon monoxide,
irritating and toxic fumes and gases, carbon
dioxide.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 107-21-1:
KW2975000
LD50/LC50:
CAS# 107-21-1:
Inhalation, rat: LC50 =10876 mg/kg; Oral, mouse: LD50
= 5500 mg/kg;
Oral, rat: LD50 = 4700 mg/kg; Skin, rabbit: LD50 = 9530
mg/kg.
Carcinogenicity:
Ethylene glycol -
ACGIH: aerosol: A4 - not classifiable as a human carcinogen
Epidemiology:
No data available.
Teratogenicity:
No data available.
Reproductive Effects:
No data available.
Neurotoxicity:
No data available.
Mutagenicity:
No data available.
Other Studies:
Please refer to
RTECS KW2975000 for additional information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Rainbow
trout: LC50 = 41000 mg/L; 96 Hr.; UnspecifiedFish:
Bluegill/Sunfish:
LC50 = 27500-41000 mg/L; 96 Hr.; UnspecifiedFish:
Goldfish: LC50
= 27500-41000 mg/L; 96 Hr.; UnspecifiedWater flea
LC50 = 46300 mg/L;
48 Hr.; UnspecifiedBacteria: Phytobacterium
phosphoreum: EC50
=620 mg/L; 30 minutes; Microtox testGoldfish LD50=
>5000mg/L/24Hr
Guppies LC50= 493,000ppm/7D Shrimp (salt water)
LC50= >100ppm/48Hr
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Chemical waste generators must determine whether a discarded chemical
is classif
as a hazardous waste.
US EPA guidelines for the classification determination are listed
in 40 CFR Part
Additionally, waste generators must consult state and local hazardous
waste regu
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
**** SECTION 14 - TRANSPORT INFORMATION ****
US DOT
No information
available
Canadian TDG
No information
available.
**** SECTION 15 - REGULATORY INFORMATION ****
US FEDERAL
TSCA
CAS# 107-21-1
is listed on the TSCA inventory.
Health & Safety Reporting
List
None of the chemicals
are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals
in this product are under a Chemical Test Rule.
Section 12b
CAS# 107-21-1:
4a/12b
TSCA Significant New Use Rule
None of the chemicals
in this material have a SNUR under TSCA.
SARA
Section 302 (RQ)
None of the chemicals
in this material have an RQ.
Section 302 (TPQ)
None of the chemicals
in this product have a TPQ.
SARA Codes
CAS # 107-21-1:
acute, chronic.
Section 313
This material
contains Ethylene glycol (CAS# 107-21-1, 99 0%),which
is subject to
the reporting requirements of Section 313 of SARA Title
III and 40 CFR
Part 372.
Clean Air Act:
CAS# 107-21-1
is listed as a hazardous air pollutant (HAP).
This material
does not contain any Class 1 Ozone depletors.
This material
does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals
in this product are listed as Hazardous
Substances under
the CWA.
None of the chemicals
in this product are listed as Priority
Pollutants under
the CWA.
None of the chemicals
in this product are listed as Toxic Pollutants
under the CWA.
OSHA:
None of the chemicals
in this product are considered highly hazardous
by OSHA.
STATE
Ethylene glycol can be found on the following
state right to know
lists: California, New Jersey, Florida, Pennsylvania,
Minnesota,
Massachusetts.
California No Significant Risk Level:
None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:
R 22 Harmful if swallowed.
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 107-21-1:
0
United Kingdom Occupational Exposure Limits
CAS# 107-21-1:
OES-United Kingdom, TWA particulate: 10 mg/m3 TWA;
vapour: 60 mg/m3
TWA
CAS# 107-21-1:
OES-United Kingdom, STEL vapour: 125 mg/m3 STEL
Canada
CAS# 107-21-1
is listed on Canada's DSL/NDSL List.
This product has
a WHMIS classification of D2A.
CAS# 107-21-1
is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 107-21-1:
OEL-AUSTRALIA:TWA 60 mg/m3;STEL 120 mg/m3
OEL-BELGIUM:STEL
50 ppm (127 mg/m3)
OEL-DENMARK:STEL
50 ppm (130 mg/m3)
OEL-DENMARK:TWA
10 mg/m3
OEL-FINLAND:TWA
10 mg/m3;STEL 20 mg/m3
OEL-FINLAND:TWA
50 ppm (125 mg/m3);STEL 75 ppm (190 mg/m3)
OEL-FRANCE:STEL
50 ppm (125 mg/m3)
OEL-HUNGARY:STEL
50 mg/m3;Skin
OEL-THE NETHERLANDS:TWA
10 mg/m3
OEL-THE NETHERLANDS:TWA
50 ppm (125 mg/m3)
OEL-RUSSIA:STEL
5 mg/m3
OEL-SWEDEN:TWA
50 ppm (130 mg/m3);STEL 75 ppm (19 mg/m3)
OEL-SWITZERLAND:TWA
1 mg/m3
OEL-SWITZERLAND:TWA
50 ppm (125 mg/m3)
OEL-UNITED KINGDOM:TWA
10 mg/m3
OEL-UNITED KINGDOM:TWA
60 mg/m3;STEL 125 mg/m3
OEL IN BULGARIA,
COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND,
SINGAPORE, VIETNAM check ACGI TLV
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 5/12/1999 Revision #2 Date: 8/02/2000
The information above is believed to be accurate
and represents the best
information currently available to us. However,
we make no warranty of
merchantability or any other warranty, express
or implied, with respect to
such information, and we assume no liability
resulting from its use. Users
should make their own investigations to determine
the suitability of the
information for their particular purposes. In
no way shall the company be
liable for any claims, losses, or damages of
any third party or for lost
profits or any special, indirect, incidental,
consequential or exemplary
damages, howsoever arising, even if the company
has been advised of
the possibility of such damages.
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